Odontoid process inclination in normal adults and in an adult population with Chiari malformation Type I
| Autor: | Lubdha M. Shah, David A. Besachio, Ziyad Khaleel |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Adolescent Population Adult population Young Adult Sex Factors CHIARI MALFORMATION TYPE I Odontoid Process medicine Humans education Aged Chiari malformation Aged 80 and over Odontoid process education.field_of_study medicine.diagnostic_test business.industry Age Factors Magnetic resonance imaging General Medicine Craniocervical junction Anatomy Middle Aged medicine.disease Magnetic Resonance Imaging Arnold-Chiari Malformation Case-Control Studies Female Tomography X-Ray Computed business Pediatric population |
| Zdroj: | Journal of Neurosurgery: Spine. 23:701-706 |
| ISSN: | 1547-5654 |
| DOI: | 10.3171/2015.3.spine14926 |
| Popis: | OBJECT Posterior odontoid process inclination has been demonstrated as a factor associated with Chiari malformation Type I (CM-I) in the pediatric population; however, no studies to date have examined this measurement in the adult CM-I population. The purpose of this study was to evaluate craniocervical junction (CCJ) measurements in adult CM-I versus a control group. METHODS The odontoid retroflexion, odontoid retroversion, odontoid height, posterior basion to C-2 line measured to the dural margin (pB-C2 line), posterior basion to C-2 line measured to the dorsal odontoid cortical margin (pB-C2* line), and clivus-canal angle measurements were retrospectively analyzed in adult patients with CM-I using MRI. These measurements were compared with normative values established from CT scans of the cervical spine in adults without CM-I. RESULTS A statistically significant difference was found between 55 adults with CM-I and 150 sex-matched controls (125 used for analysis) in the mean clivus-canal angle and the mean pB-C2 line. CONCLUSIONS These data suggest that there are sex-specific differences with respect to measurements at the CCJ between men and women, with women showing a more posteriorly inclined odontoid process. There were also differences between the CM-I and control groups: a more acute clivus-canal angle was associated with CM-I in the adult population. These CCJ findings could have an influence on presurgical planning. |
| Databáze: | OpenAIRE |
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