Prevalence of clinic-defined food allergy in early adolescence: The SchoolNuts study
| Autor: | Angela Pezic, George C Patton, Katrina J. Allen, Rachel L. Peters, Maia Brewerton, Michael J. Field, Jennifer J. Koplin, Jo A Douglass, Mimi L.K. Tang, Mari Sasaki, Shyamali C. Dharmage, Susan M Sawyer, Peter Vuillermin, Vicki McWilliam, Lyle C. Gurrin |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Allergy Adolescent Cross-sectional study Immunology Population Peanut allergy Adolescent age 03 medical and health sciences 0302 clinical medicine Food allergy Surveys and Questionnaires medicine Prevalence Immunology and Allergy Humans 030212 general & internal medicine education Child Skin Tests education.field_of_study Oral food challenge business.industry digestive oral and skin physiology Allergens medicine.disease Cross-Sectional Studies Phenotype 030228 respiratory system Social Class Food Population Surveillance Tree nut allergy Female business Food Hypersensitivity |
| Zdroj: | The Journal of allergy and clinical immunology. 141(1) |
| ISSN: | 1097-6825 |
| Popis: | Background Rising rates of food-induced anaphylaxis have recently been shown in the adolescent age group, following earlier descriptions of a rise in children younger than 5 years. However, few population-based studies have examined the prevalence of food allergy in adolescence using objective measures such as oral food challenge (OFC). Objective We sought to determine the prevalence of food allergy among a population-based sample of 10- to 14-year-old adolescents using clinical evaluation including OFC to confirm the diagnosis. Methods Schools were randomly selected from greater metropolitan Melbourne, Australia. Students aged 10 to 14 years, and their parents, were asked to complete a questionnaire regarding the adolescent's food allergy or food-related reactions. Clinic evaluation, which consisted of skin prick tests and OFC where eligible, was undertaken if students were suspected to have current food allergy from parent response. Among 9816 students assessed, 5016 had complete parent response and clinic evaluation when eligible. An additional 4800 students had student questionnaires only. Results The prevalence of clinic-defined current food allergy based on history, sensitization data, and OFC results was 4.5% (95% CI, 3.9-5.1), with the most common food triggers being peanut, 2.7% (95% CI, 2.3-3.2), and tree nut, 2.3% (95% CI, 1.9-2.8). Among the additional group of 4800 adolescents who had only self-reported food allergy status available, the prevalence of self-reported current food allergy was 5.5% (95% CI, 4.9-6.2), with peanut, 2.8% (95% CI, 2.3-3.3), and tree nut, 2.3% (95% CI, 1.9-2.8), the most common. Conclusions Approximately 1 in 20 10- to 14-year-old school students in Melbourne has current food allergy. This high prevalence suggests that the previously reported rise in food-induced anaphylaxis in this age group may reflect an increasing prevalence of food allergy rather than simply increased reporting of anaphylaxis. |
| Databáze: | OpenAIRE |
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