A comparative study of vesicular stomatitis virus and its plaque type mutant
| Autor: | Isaac L. Shechmeister, Fern Probstmeyer |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Immunodiffusion
Mutant Wild type General Medicine Biology Virus Replication Pathogenicity biology.organism_classification Virology Vesicular stomatitis Indiana virus Cytopathogenic Effect Viral Neutralization Tests Vesicular stomatitis virus Culture Techniques Mutation Centrifugation Density Gradient Plaque type Antigens Immunoelectrophoresis HeLa Cells |
| Zdroj: | Archiv f�r die gesamte Virusforschung. 23:79-88 |
| ISSN: | 1432-8798 0304-8608 |
| DOI: | 10.1007/bf01242116 |
| Popis: | This comparative study shows that the plaque mutant, p-1a, is antigenically identical to the wild type parent vesicular stomatitis virus. Several properties of the mutant are strikingly different from those of the parent strain, including plaque size, growth rate, pathogenicity and the number of bands as demonstrated in density gradients. However, the immunodiffusion and immunoelectrophoretic properties of these viruses appear identical. Since the mutant, p-1a, is stable and relatively easy to handle in the laboratory, it may become a useful agent in viral genetic studies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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