Adjuvant recMAGE-A3 Immunotherapy After Cystectomy for Muscle-invasive Bladder Cancer: Lessons Learned from the Phase 2 MAGNOLIA Clinical Trial

Autor:	Cristian Surcel, Raymond Schipper, Igor Korneyev, Marc Colombel, Pavel Yakovlev, Renzo Colombo, Luis Martínez-Piñeiro, Wim P.J. Witjes, Piotr Radziszewski, Axel Heidenreich, Christien Caris, J. Alfred Witjes, Peter F.A. Mulders, Marko Babjuk
Rok vydání:	2019
Předmět:	Oncology medicine.medical_specialty Urology medicine.medical_treatment education 030232 urology & nephrology Cystectomy 03 medical and health sciences All institutes and research themes of the Radboud University Medical Center Clinical Trials Phase II as Topic 0302 clinical medicine Double-Blind Method Antigens Neoplasm Internal medicine Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15] Humans Medicine Neoplasm Invasiveness Randomized Controlled Trials as Topic Chemotherapy Bladder cancer business.industry Muscle invasive Perioperative Immunotherapy medicine.disease Recombinant Proteins Neoplasm Proteins Clinical trial Urinary Bladder Neoplasms Chemotherapy Adjuvant Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] 030220 oncology & carcinogenesis Early Termination of Clinical Trials business Adjuvant
Zdroj:	European Urology Focus, 5, 849-852 European Urology Focus, 5, 5, pp. 849-852
ISSN:	2405-4569
Popis:	The MAGNOLIA study, investigating the concept of perioperative immunotherapy in muscle- invasive bladder cancer, was prematurely terminated. The lessons learned that should be considered before initiating and conducting future clinical trials in this field are highlighted.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cc058a00e96efdb02758d41c115530 https://doi.org/10.1016/j.euf.2018.02.005 Zobrazit plný text záznamu Full Text from ScienceDirect