Analytical model for managing hypotony after implantation surgery of a glaucoma drainage device
Autor: | José María Montanero, Julian Garcia-Feijoo, B. Kudiesh, José Ignacio Fernández-Vigo, R. Agujetas |
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Rok vydání: | 2021 |
Předmět: |
Intraocular pressure
medicine.medical_specialty Tube diameter genetic structures Glaucoma Ocular Hypotension Models Biological 01 natural sciences 010305 fluids & plasmas Aqueous humor flow Aqueous Humor Prosthesis Implantation 03 medical and health sciences Filtering bleb 0302 clinical medicine Suture (anatomy) 0103 physical sciences medicine Humans Tube (fluid conveyance) Glaucoma Drainage Implants Original Paper business.industry Mechanical Engineering Glaucoma drainage device medicine.disease eye diseases Surgery Modeling and Simulation 030221 ophthalmology & optometry Glaucom sense organs Bleb (medicine) business Biotechnology |
Zdroj: | Biomechanics and Modeling in Mechanobiology |
ISSN: | 1617-7940 1617-7959 |
DOI: | 10.1007/s10237-021-01494-w |
Popis: | The main aim of glaucoma treatment is to reduce the intraocular pressure (IOP). One of the most common surgical treatments of glaucoma is the implantation of a glaucoma drainage device to drain the aqueous humor from the anterior chamber to a filtration bleb, where the aqueous humor is absorbed. In some cases, the excess of drainage causes ocular hypotony, which constitutes a sight-threatening complication. To prevent hypotony after this intervention, surgeons frequently introduce a suture into the device tube, which increases the hydraulic resistance of the tube and, therefore, the IOP. This study aims to provide an analytical model to correct hypotony following implantation surgery of a glaucoma drainage device, which may help glaucoma surgeons decide on hypotony treatment. The results indicate that the IOP after implanting a cylindrical tube around 300 μm in diameter is essentially the same as that built up in the filtering bleb and can hardly be controlled by introducing a straight suture unless the suture diameter is slightly lower than that of the tube. On the contrary, when the tube diameter is smaller than, for example, 100 μm, significant reductions of the IOP can be obtained by introducing a thin suture into the tube. |
Databáze: | OpenAIRE |
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