Changes in genetic types and population dynamics of Moraxella catarrhalis in hospitalised children are not associated with an exacerbation of existing disease
| Autor: | Kimberly Eadie, Jan A. Hazelzet, John P. Hays, Cees M. Verduin, A. van Belkum, Henri A. Verbrugh |
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| Přispěvatelé: | Medical Microbiology & Infectious Diseases, Pediatrics |
| Rok vydání: | 2003 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Adolescent Exacerbation Population Disease Biology Microbiology Moraxella catarrhalis Internal medicine Moraxella (Branhamella) catarrhalis Prevalence medicine Humans Typing Child education Netherlands Retrospective Studies Cross Infection education.field_of_study Genetic Variation Infant Retrospective cohort study General Medicine biology.organism_classification Bacterial Typing Techniques Electrophoresis Gel Pulsed-Field Hospitalization El Niño Child Preschool Immunology Gram-Negative Bacterial Infections |
| Zdroj: | Journal of Medical Microbiology, 52, 815-820. Microbiology Society |
| ISSN: | 0022-2615 |
| Popis: | Pulsed-field gel electrophoresis typing was performed on a retrospective set of 129 Moraxella catarrhalis isolates obtained over a 20 month period from 70 children admitted to, or presenting at, the Erasmus University Medical Center, Rotterdam, The Netherlands. The mean age of the children (at the end of the study) was 2.5 years, with a range of 6 months to 15 years. Fifty-one different M. catarrhalis types were isolated from the hospitalized children, with 31 % (22/70) being infected with two particularly prevalent M. catarrhalis types. These two prevalent types also exhibited different protein profiles. The majority (72%; 16/22) of the children infected with these two predominant types had spent at least 1 week on two paediatric intensive care wards. No exacerbation of existing disease or new disease was observed in children who experienced M. catarrhalis type changes. |
| Databáze: | OpenAIRE |
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