High-risk human papilloma viruses (HPVs) were not detected in the benign skin lesions of a small number of children
| Autor: | Demetrios A. Spandidos, Ioannis N. Mammas, C Michael, G. Sourvinos |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Pathology medicine.medical_specialty Skin Neoplasms Adolescent Pilot Projects Polymerase Chain Reaction Virus law.invention law medicine Humans Oral mucosa Child Polymerase chain reaction Human papillomavirus 16 Human papillomavirus 18 Transmission (medicine) business.industry Human papillomavirus 11 virus diseases General Medicine medicine.disease female genital diseases and pregnancy complications Numero sign medicine.anatomical_structure Sexual abuse Case-Control Studies Pediatrics Perinatology and Child Health DNA Viral Papilloma Female Warts business Autoinoculation |
| Zdroj: | Acta paediatrica (Oslo, Norway : 1992). 97(12) |
| ISSN: | 1651-2227 |
| Popis: | Aim: Human papilloma virus (HPV) can be transmitted via sexual as well as nonsexual routes. Recently, ‘high-risk’ HPVs were detected in the oral mucosa of children in whose cases there was no suspicion of sexual abuse. This implies that HPV 16 and 18 have additional nonsexual modes of transmission in childhood, such as vertical transmission and autoinoculation. Methods: Using polymerase chain reaction (PCR) assays, we examined the skin tissues of 12 children with benign skin lesions, aged between 6 and 13 years, for the presence of HPV. Results: Among 12 biopsy skin specimens, no ‘high-risk’ HPV DNA was detected. Specific PCRs for HPV DNA 16 and 18 were also negative. Conclusion: This preliminary case-control study indicates the absence of mucosal ‘high-risk’ HPV types in the benign skin lesions of children. |
| Databáze: | OpenAIRE |
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