Practical guidance for clinical laboratories for SARS-CoV-2 serology testing
| Autor: | Carmen L. Charlton, Jonathan B. Gubbay, Amanda Lang, Heidi Wood, Paul Levett, Jamil N. Kanji, Antonia Dibernardo, Jason Robinson, L. Robbin Lindsay, Derek R. Stein, Inna Sekirov, Muhammad Morshed, Todd Hatchette, Michael A. Drebot, Nadia El-Gabalawy, Christian Therrien, Lei Jiao, Vanessa Tran, Julianne V. Kus, Carla Osiowy, Jessica D. Forbes |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
education.field_of_study business.industry Public health Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Population Diagnostic test Acute infection General Medicine Diagnostic Testing Infectious and parasitic diseases RC109-216 serological testing Serology Clinical microbiology sars-cov-2 covid-19 serology algorithms medicine Intensive care medicine business education Antibody screening |
| Zdroj: | Canada Communicable Disease Report, Vol 47, Iss 4, Pp 171-183 (2021) Can Commun Dis Rep |
| ISSN: | 1481-8531 |
| Popis: | The landscape of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic testing is rapidly evolving. While serology testing has limited diagnostic capacity for acute infection, its role in providing population-based information on positivity rates and informing evidence-based decision making for public health recommendations is increasing. With the global availability of vaccines, there is increasing pressure on clinical laboratories to provide antibody screening and result interpretation for vaccinated and non-vaccinated individuals. Here we present the most up-to-date data on SARS-CoV-2 antibody timelines, including the longevity of antibodies, and the production and detection of neutralizing antibodies. Additionally, we provide practical guidance for clinical microbiology laboratories to both verify commercial serology assays and choose appropriate testing algorithms for their local populations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|