Oral squamous cell carcinoma with microscopic extracapsular spread in the cervical lymph nodes
| Autor: | Takumi Hasegawa, Takahide Komori, Takashi Shigeta, Chihoko Hirai, Yasuyuki Shibuya, Masaya Akashi, Yumi Ohtsuki, Tsutomu Minamikawa |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology medicine.medical_treatment Urology Resection medicine Overall survival Humans Basal cell Survival rate Aged Neoplasm Staging Aged 80 and over business.industry Poorly differentiated carcinoma Neck dissection Middle Aged Prognosis Combined Modality Therapy Survival Rate medicine.anatomical_structure Otorhinolaryngology Cervical lymph nodes Lymphatic Metastasis Carcinoma Squamous Cell Neck Dissection Female Mouth Neoplasms Surgery Neoplasm Grading Oral Surgery business |
| Zdroj: | International Journal of Oral and Maxillofacial Surgery. 43:387-392 |
| ISSN: | 0901-5027 |
| Popis: | The purpose of this study was to determine the detailed background of cases of oral squamous cell carcinoma (OSCC) with microscopic extracapsular spread (ECS) in the cervical lymph nodes. The cases of 78 patients with primary OSCC, who attended hospital from October 2007 to July 2011 and underwent resection of the primary tumour with neck dissection, were reviewed. The subjects were classified into three categories: pN0, pN+/ECS-, and pN+/ECS+; the outcomes of pN+/ECS+ patients were compared in detail with those of the other categories. Thirty-one cases (39.7%) were pN0, 25 cases (32.1%) were pN+/ECS-, and 22 cases (28.2%) were pN+/ECS+. The 3-year overall survival rate was 82.1% in pN0, 74.1% in pN+/ECS-, and 39.8% in pN+/ECS+ (pN0 vs. pN+/ECS+, P=0.0004; pN+/ECS- vs. pN+/ECS+, P=0.0086). The 3-year disease-specific survival rate was 96.2% in pN0, 77.2% in pN+/ECS-, and 39.8% in pN+/ECS+ (pN0 vs. pN+/ECS+, P |
| Databáze: | OpenAIRE |
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