Acute rheumatic fever outbreak in southern central European country
| Autor: | Luka Kopač, Tadej Avcin, Blaž Kosmač, Samo Vesel, Rina Rus, Natalija Krajnc, Nataša Toplak, Matjaž Homan, Urška Kočevar |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Fever Slovenia Prevalence Penicillins 030204 cardiovascular system & hematology Disease Outbreaks Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Epidemiology Secondary Prevention Humans Medicine 030212 general & internal medicine Child Intensive care medicine Retrospective Studies business.industry Incidence Incidence (epidemiology) Outbreak Carditis Chorea medicine.disease Anti-Bacterial Agents Pediatrics Perinatology and Child Health Rheumatic fever Female Rheumatic Fever medicine.symptom business Rare disease |
| Zdroj: | European Journal of Pediatrics. 176:23-29 |
| ISSN: | 1432-1076 0340-6199 |
| DOI: | 10.1007/s00431-016-2801-z |
| Popis: | A decline in the incidence of acute rheumatic fever (ARF) in developed countries over the past century can be attributed to the improved public hygiene and to widespread use of antibiotics. ARF seemed to be a rare disease in southern central European country, Slovenia, up to 2010 when we noticed an increase in the number of patients with ARF. In order to assess the current incidence of ARF, we performed a retrospective study of all patients with ARF treated at the University Children's Hospital Ljubljana from January 2008 until the end of December 2014. In a period of 7 years, 19 patients with ARF were identified. The estimated annual incidence of ARF during the study period was 1.25 cases per 100,000 children. Carditis was present in all patients, arthritis in 37 % and Sydenham chorea in 32 %.Recent ARF outbreak in Slovenia revealed that this disease is still present in southern central Europe with an estimated annual incidence of 1.25 cases per 100,000 children. Unrecognized or inadequately treated ARF could be the cause of acquired heart disease and must be even nowadays included among the differential diagnoses in a febrile child with arthritis, heart murmur or movement disorder. What is Known: • Acute rheumatic fever (ARF) is diagnosed based on the major and minor Jones Criteria. • A decline in the incidence of ARF in developed countries over the past century can be attributed to the improved public hygiene and to widespread use of antibiotics. What is New: • In the last decade, an increase in the incidence of ARF was observed in Slovenia which has a central European geographic position. • Our paper highlights the importance of including ARF in the differential diagnosis of a febrile child with arthritis/arthralgia and/or heart murmur and/or acute chorea. |
| Databáze: | OpenAIRE |
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