The microanatomical environment of the subthalamic nucleus
| Autor: | Emile A. M. Beuls, Peter Adriaensens, Marjan Vandersteen, Veerle Visser-Vandewalle, Yasin Temel, Kim Rijkers, Linda Vanormelingen, Jan Gelan |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.diagnostic_test
business.industry Slice thickness 3D reconstruction Magnetic resonance imaging Brain tissue Anatomy Human brain Magnetic Resonance Imaging Mr imaging nervous system diseases Subthalamic nucleus surgical procedures operative medicine.anatomical_structure nervous system Subthalamic Nucleus Humans Medicine business Neuroanatomy |
| Zdroj: | Journal of Neurosurgery. 107:198-201 |
| ISSN: | 0022-3085 |
| DOI: | 10.3171/jns-07/07/0198 |
| Popis: | ✓High-frequency stimulation of the subthalamic nucleus (STN) is a widely performed method to treat advanced Parkinson disease. Due to the limitations of current imaging techniques, the 3D microanatomy of the STN and its surrounding structures in the mesencephalon are not well known. Using images they obtained using a 9.4-tesla magnetic resonance (MR) imaging unit, the authors developed a 3D reconstruction of the STN and its immediate surroundings. During the postmortem investigation of a human brain, a sample of tissue in the area around the STN was isolated. This brain tissue was scanned in the three orthogonal planes at 1-mm slice thickness. The images generated were compared with photographs of conventionally stained brain tissue slices in different neuroanatomical books, and a 3D reconstruction was made. High-field MR imaging is an appropriate method for visualizing the microanatomy of the STN and its surroundings. The images allow an optimal analysis of the microenvironment of the STN in the three orthogonal planes and can be used for 3D reconstructions of this area with possible clinical applications in the future. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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