Smartphone based optical spectrometer for diffusive reflectance spectroscopic measurement of hemoglobin
| Autor: | Zhiwen Liu, Xiangqian Hong, Vivek Krishna Nagarajan, Chenji Zhang, Perry S. Edwards, Baigang Zhang, Bing Yu |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Diffuse reflectance infrared fourier transform Resolution (mass spectrometry) Point-of-Care Systems Imaging spectrometer lcsh:Medicine 01 natural sciences Article law.invention 010309 optics Hemoglobins Optics law 0103 physical sciences Humans lcsh:Science Spectrograph Multidisciplinary Spectrometer business.industry Phantoms Imaging 010401 analytical chemistry Near-infrared spectroscopy lcsh:R Reflectivity Optical spectrometer 0104 chemical sciences Spectrophotometry lcsh:Q Smartphone business |
| Zdroj: | Scientific Reports Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017) |
| ISSN: | 2045-2322 |
| Popis: | We report a miniature, visible to near infrared G-Fresnel spectrometer that contains a complete spectrograph system, including the detection hardware and connects with a smartphone through a microUSB port for operational control. The smartphone spectrometer is able to achieve a resolution of ~5 nm in a wavelength range from 400 nm to 1000 nm. We further developed a diffuse reflectance spectroscopy system using the smartphone spectrometer and demonstrated the capability of hemoglobin measurement. Proof of concept studies of tissue phantoms yielded a mean error of 9.2% on hemoglobin concentration measurement, comparable to that obtained with a commercial benchtop spectrometer. The smartphone G-Fresnel spectrometer and the diffuse reflectance spectroscopy system can potentially enable new point-of-care opportunities, such as cancer screening. |
| Databáze: | OpenAIRE |
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