Identification of the cockroach neuropeptide Pea-CAH-II as a second adipokinetic hormone in the firebug Pyrrhocoris apterus
| Autor: | Luděk Lepša, Dalibor Kodrík, Petr Šimek, Radomír Socha |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Physiology Neuropeptide Cockroaches Peptide Firebug Biology Biochemistry Heteroptera Cellular and Molecular Neuroscience Endocrinology biology.animal Internal medicine medicine Animals Adipokinetic hormone chemistry.chemical_classification Cockroach Neuropeptides Lipid mobilization Pyrrhocoris biology.organism_classification Pyrrolidonecarboxylic Acid Amino acid chemistry Insect Hormones |
| Zdroj: | Peptides. 23:585-587 |
| ISSN: | 0196-9781 |
| DOI: | 10.1016/s0196-9781(01)00627-1 |
| Popis: | A new member of the AKH/RPCH family was isolated from the corpora cardiaca of the firebug Pyrrhocoris apterus. It is the second adipokinetic peptide identified in this species. The peptide was characterized and its structure was deduced from the multiple MSN electrospray mass spectra as that of an octapeptide with the sequence pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-NH2. The peptide differs from the original P. apterus AKH (Pya-AKH) by one amino acid in position 3. Topical application and/or injection of the peptide induced lipid mobilization, but was inactive in mobilization of carbohydrates. |
| Databáze: | OpenAIRE |
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