In vitro assembly of cytoplasmic microtubules
| Autor: | Serge N Timasheff, Linda M Grisham |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Anions
GTP' Macromolecular Substances Nerve Tissue Proteins macromolecular substances GTPase Biochemistry Microtubules GTP Phosphohydrolases Microtubule Tubulin Animals Nucleotide Kinase activity chemistry.chemical_classification biology Brain Rho Factor Molecular Weight Kinetics chemistry Cytoplasm biology.protein Biophysics Solvents Phosphorylation Guanosine Triphosphate |
| Zdroj: | Annual review of biochemistry. 49 |
| ISSN: | 0066-4154 |
| Popis: | PERSPECTIVES AND SUMMARY . METHODOLOGY .... : . . EQUILIBRIA IN THE ASSEMBLY PROCESS . Nucleated Polymerization Model . Is Tubulin Competent to Assemble? ; . . . . . ... . . . . . ... . . . . . . . . . . . . . .. CHEMICAL CHARACTERISTICS OF THE MICROTUBULE ASSEMBLY PROCESS .. . . . . . . . . ..... . . . . . . . . . . . . . . ........ . . . . . . . . . . . . . . . . . . ..... . . . . . . . .. . . . . . . . . . . . ......... .. . Role of Solvent Components . Role of Nontubulin Proteins . T factor : ..... ......... ....... . . ..... . Map or HMW fraction .. Are T and HMW-MAPs specijic? . Role of Nucleotides . Involvement of GTP . Mechanism of GTP action . GTPase Activity of tubulin ..... ........ . . . . ... ..... . . . . ..... . . . . .... . . . . . . ... . . . ... . . . . . . . . . ... . . ... . . . . . ... ..... . Role of Covalent Modifications of Tubulin . . Phosphorylation and kinase activity . SH groups . Tyroslation ... . MECHANISM OF MICROTUBULE ASSEMBLy .. Initiation . |
| Databáze: | OpenAIRE |
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