Analysis of Phthalates and Alternative Plasticizers in Gloves by Gas Chromatography–Mass Spectrometry and Liquid Chromatography–UV Detection: A Comparative Study
| Autor: | Romain Regnault, Tiphaine Rogez-Florent, Cécile Danel, Christelle Monteil, Philippe Vérité, Marie Lecoeur, Kelly Poitou, Catherine Foulon |
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| Přispěvatelé: | Aliments Bioprocédés Toxicologie Environnements (ABTE), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 (GRITA), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille, Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
gloves
Health Toxicology and Mutagenesis TP1-1185 010501 environmental sciences Toxic substance Toxicology 01 natural sciences Article law.invention law Protective gloves [CHIM.ANAL]Chemical Sciences/Analytical chemistry alternative plasticizers Sample preparation liquid chromatography–diode array detector (HPLC–DAD) 0105 earth and related environmental sciences phthalates Chemical Health and Safety Chromatography Chemistry Chemical technology 010401 analytical chemistry Plasticizer 0104 chemical sciences Neoprene gas chromatography–mass spectrometry (GC–MS) Gas chromatography–mass spectrometry Uv detection |
| Zdroj: | Toxics, Vol 9, Iss 200, p 200 (2021) Toxics Toxics, MDPI, 2021, 9 (9), pp.200. ⟨10.3390/toxics9090200⟩ Toxics, 2021, 9 (9), pp.200. ⟨10.3390/toxics9090200⟩ Volume 9 Issue 9 Pages: 200 |
| ISSN: | 2305-6304 |
| DOI: | 10.3390/toxics9090200⟩ |
| Popis: | International audience; Gloves represent an essential feature for hand protection because it is a requirement in the professional framework to comply with both hand hygiene standards and the principles of good laboratory practice. Despite their wide use, there is a knowledge gap regarding their composition, including phthalates. The purpose of the present study was to develop two orthogonal methods, GC–MS and HPLC–DAD, for the screening of plasticizers in gloves. Performances of these two methods were compared in terms of ease of use, number of analyzed plasticizers, and sample preparation. The two methods were validated and applied for the identification and quantification of plasticizers in ten gloves made with different materials (vinyl, nitrile, latex, and neoprene). Results revealed the presence of three main ones: DEHP, DEHT, and DINP. Additionally, the contents of plasticizers were extremely variable, depending on the glove material. As expected, the results point out a predominant use of plasticizers in vinyl gloves with an amount that should be of concern. While DEHP is classified as a toxic substance for reproduction 1B, it was, however, quantified in the ten different glove samples studied. This study provides new data regarding the plasticizers’ content in protective gloves, which could be useful for risk assessment. |
| Databáze: | OpenAIRE |
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