| Autor: |
Miikka, Lehtonen, Jorma, Sormunen, Marie, Hjälm-Eriksson, Camilla, Thellenberg-Karlsson, Teppo, Huttunen, Claes, Ginman, Pirkko-Liisa, Kellokumpu-Lehtinen |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Anticancer research. 42(1) |
| ISSN: |
1791-7530 |
| Popis: |
The goal of this study was to investigate whether health-related quality of life (HRQoL) was affected in patients with high- or intermediate-risk localized prostate cancer treated with docetaxel following radiation therapy (RT).A total of 376 patients treated with RT and androgen deprivation were randomized to receive 6 cycles of docetaxel 75 mg/mFACT-P scores decreased in Arm A at the end of treatment and remained unchanged in Arm B (p0.0001). The HRQoL scores in Arm A matched Arm B in the 1-year follow-up (p=0.0528) and remained similar in further follow-up.Docetaxel transiently decreased HRQoL during chemotherapy but not after treatment for up to four years of follow-up. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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