Primary diffuse leptomeningeal gliomatosis simulating tuberculous meningitis
| Autor: | N Balakas, J H Rees, T Revesz, M Luxsuwong, G Giovanonni, S F Hain, A Agathonikou, C P Panayiotopoulos |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Short Report Tuberculous meningitis Central nervous system disease Cerebrospinal fluid Cytology Biopsy Meningeal Neoplasms Medicine Humans Meningeal Neoplasm Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Glioma Middle Aged medicine.disease Hydrocephalus Psychiatry and Mental health Tuberculosis Meningeal Surgery Female Neurology (clinical) business Meningitis |
| Zdroj: | Journal of neurology, neurosurgery, and psychiatry. 70(1) |
| ISSN: | 0022-3050 |
| Popis: | Three patients are reported on who presented with communicating hydrocephalus due to presumed tuberculous meningitis. Subsequent clinical deterioration despite antituberculous chemotherapy prompted reassessment with FDG-PET scanning and meningeal biopsy in one case and repeat CSF cytology with special staining in the second. The third patient died and postmortem confirmed a diagnosis of primary diffuse leptomeningeal gliomatosis. In the first two patients, MRI of the entire neuraxis showed no evidence of a primary intraparenchymal tumour. These cases emphasise the need for repeated reassessment in patients with culture negative lymphocytic meningitis. In addition, this is the first report of FDG-PET scanning in leptomeningeal gliomatosis. |
| Databáze: | OpenAIRE |
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