The neuropharmacological restoration of cognitive functions of cats following a lesion to the basal nuclei of the forebrain (Meynert's nucleus)
| Autor: | Yu. K. Mukhina, E. I. Mukhin, T. N. Nabieva |
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| Rok vydání: | 1993 |
| Předmět: |
Male
Dopamine Stimulation Lesion Basal (phylogenetics) Cognition Substantia Innominata medicine Animals Ibotenic Acid Problem Solving gamma-Aminobutyric Acid CATS General Neuroscience Dopaminergic Parasympatholytics Acetylcholine Generalization Stimulus Forebrain Cats Conditioning Operant GABAergic Cholinergic Female medicine.symptom Psychology Neuroscience |
| Zdroj: | Neuroscience and Behavioral Physiology. 23:344-351 |
| ISSN: | 1573-899X 0097-0549 |
| DOI: | 10.1007/bf01183027 |
| Popis: | The functions of generalization and abstraction in an experimental model of Alzheimer's disease (the lesion of Meynert's nuclei in cats) were studied against the background of stimulation and inhibition of the cholinergic, GABAergic, and dopaminergic systems of the brain. It was demonstrated that the cholinergic system is a key system for the formation of the function of generalization, the dopaminergic system improves simple forms of learning, while the GABAergic system is actively involved in the establishment of complex types of associations. |
| Databáze: | OpenAIRE |
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