Simultaneous pathological findings in biopsy specimens of patients with surgically resected lung carcinoids and their role in survival
| Autor: | Vasiliki Georgakopoulou, Eleftherios Zygouris, Petros Papalexis, Aikaterini Gkoufa, Christos Damaskos, Aikaterini Pierrakou, Konstantinos Mantzouranis, Serafeim Chlapoutakis, Aikaterini Aravantinou‑Fatorou, Pagona Sklapani, Nikolaos Trakas, Jim Janinis, Jubrail Dahabreh, Demetrios Spandidos |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Oncology Letters. 24 |
| ISSN: | 1792-1082 1792-1074 |
| DOI: | 10.3892/ol.2022.13433 |
| Popis: | Pulmonary carcinoid tumors are rare, low-grade malignant tumors that constitute 1-2% of all lung tumors. The present study aimed to describe the simultaneous pathological findings in biopsy specimens of patients with surgically resected lung carcinoids and determine their association with survival rates. For this purpose, 108 patients with resected carcinoid lung tumors were followed-up for 96 months and analyzed for simultaneous pathological findings in biopsy specimens. Among these, simultaneous pathological findings were found in 82 patients. The association between these findings and patient survival rates was evaluated. Atelectasis was a simultaneous finding in 52.4% of the patients, desquamative interstitial pneumonia (DIP) in 13.4%, emphysema in 24.4% and bronchiectasis in 9.8%. The survival rate was 100% for the patients with atelectasis, 81.8% for the patients with DIP, 90% for the patients with emphysema and 75% for the patients with bronchiectasis (P0.05). According to the univariate analysis, the type of carcinoid was associated with patient survival with better survival rates for patients with typical carcinoids, while age, sex, stage and simultaneous pathological findings were not associated with patient survival. On the whole, there was a statistically significant difference in the survival rates of patients with resected lung carcinoids with different simultaneous pathological findings. However, further studies are warranted to assess the role of these findings in the survival of these patients. |
| Databáze: | OpenAIRE |
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