Fibrinopeptide A and sudden coronary death
| Autor: | Yvonne Stirling, T W Meade, T.P. Welch, D. J. Howarth, M.R. Crompton |
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| Rok vydání: | 1984 |
| Předmět: |
Male
medicine.medical_specialty Resuscitation Time Factors Fibrinopeptide A Coronary Disease Punctures Sudden death Death Sudden Internal medicine medicine Humans cardiovascular diseases Aged Sudden coronary death Massage business.industry Thrombin Fibrinogen Heart General Medicine Middle Aged Coronary heart disease Past history Surgery Cardiology Ischaemic heart disease Female business |
| Zdroj: | Lancet (London, England). 2(8403) |
| ISSN: | 0140-6736 |
| Popis: | Fibrinopeptide A (FPA) concentrations were measured in blood taken by direct cardiac puncture from 31 patients who had died suddenly of ischaemic heart disease (IHD) and from 8 patients who had died suddenly of other causes. Mean FPA concentration in the IHD group was five times higher than that in the non-IHD group. This difference was almost entirely due to the high FPA level in the IHD subjects with a history of the disease. The FPA difference between the IHD and non-IHD groups is unlikely to have been due to differences in methods of resuscitation. A possible interpretation of the findings is that thrombin production causes or aggravates the course of events leading to sudden IHD death, particularly in subjects with a past history of IHD. |
| Databáze: | OpenAIRE |
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