Clinical Stability in Human Immunodeficiency Virus–Infected Patients with Community‐Acquired Pneumonia
| Autor: | Nicola Petrosillo, Luigia Scudeller, Leonardo Pagani, Barbara Cadeo, Liana Signorini, G. Carosi, Pierluigi Viale, Enrico Girardi |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty Respiratory rate Vital signs HIV Infections Acquired immunodeficiency syndrome (AIDS) Community-acquired pneumonia Internal medicine medicine Humans Sida biology business.industry Respiratory disease HIV Pneumonia biology.organism_classification medicine.disease Surgery Community-Acquired Infections Infectious Diseases Blood pressure Tasa Female business |
| Zdroj: | Clinical Infectious Diseases. 38:271-279 |
| ISSN: | 1537-6591 1058-4838 |
| Popis: | Clinical stability (CS), defined as normalization of vital signs, is often used to manage inpatients with community-acquired pneumonia (CAP). The main objective of our study was to identify a reliable definition of CS for human immunodeficiency virus (HIV)‐positive patients with CAP. During an 18-month period, 437 HIV-positive Italian inpatients with CAP were enrolled in the study. We used 3 definitions of CS (from a less conservative [definition 1] to a more conservative [definition 3] definition) based on combinations of different thresholds for vital signs. Assessments were performed at admission and daily during the hospital stay. For the 3 definitions, 14.9%, 8.0%, and 4.8% of patients were stable at baseline, with deterioration after reaching CS in 7.16%, 4.76%, and 2.05%, respectively. The 8 patients whose conditions deteriorated after reaching CS definition 3 (systolic blood pressure, 190 mm Hg; pulse, !90 beats/min; respiratory rate, !20 breaths/min; oxygen saturation, 190%; temperature, !37� C; ability to eat; and normal mental status) survived and were discharged from the hospital. The more conservative definition of CS appears to be reliable for the management of HIV-infected patients with CAP. |
| Databáze: | OpenAIRE |
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