Role of the nervous system in cancers: a review
| Autor: | Yicheng Chen, Liya Wang, Huan Wang, Zeyi Lu, Hao Zhang, Liqun Xia, Mingchao Wang, Gonghui Li, Qiming Zheng, Lifeng Ding |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Nervous system Cancer microenvironment Cancer Research Immunology Perineural invasion Review Article 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Targeted therapies Prostate Medicine Pathological RC254-282 QH573-671 business.industry Cancer Neoplasms. Tumors. Oncology. Including cancer and carcinogens Cell Biology medicine.disease Crosstalk (biology) 030104 developmental biology medicine.anatomical_structure Tumor progression 030220 oncology & carcinogenesis Cancer research business Cytology Reprogramming |
| Zdroj: | Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021) Cell Death Discovery |
| ISSN: | 2058-7716 |
| Popis: | Nerves are important pathological elements of the microenvironment of tumors, including those in pancreatic, colon and rectal, prostate, head and neck, and breast cancers. Recent studies have associated perineural invasion with tumor progression and poor outcomes. In turn, tumors drive the reprogramming of neurons to recruit new nerve fibers. Therefore, the crosstalk between nerves and tumors is the hot topic and trend in current cancer investigations. Herein, we reviewed recent studies presenting direct supporting evidences for a better understanding of nerve–tumor interactions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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