Evidence and consensus based GKJR guidelines for the treatment of juvenile idiopathic arthritis
| Autor: | Norbert Wagner, G Dueckers, Ina Kopp, Tim Niehues, Hartmut Michels, Marianne Spamer, Nihal Guellac, Michael Frosch, Martin Arbogast, Guenther E. Dannecker, Arnold Illhardt, Ruediger Krauspe, Barbara Markus, Wolfram Singendonk, Helmut Sitter, Matthias Schneider, G. Horneff, Gerd Ganser, Arnd Heiligenhaus, Ivan Foeldvari |
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| Rok vydání: | 2012 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty Consensus Children and adolescents Adolescent Consensus Development Conferences as Topic Immunology Alternative medicine MEDLINE Arthritis Guideline Young Adult Pharmacotherapy Nominal group technique medicine Humans Immunology and Allergy Young adult Child Glucocorticoids Evidence-Based Medicine business.industry Anti-Inflammatory Agents Non-Steroidal Antibodies Monoclonal Evidence-based medicine Juvenile idiopathic arthritis medicine.disease Combined Modality Therapy Arthritis Juvenile Treatment Methotrexate Child Preschool Family medicine Practice Guidelines as Topic Physical therapy business |
| Zdroj: | Clinical Immunology. 142:176-193 |
| ISSN: | 1521-6616 |
| Popis: | Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and adolescents. Immunomodulatory drugs are used frequently in its treatment. Using the nominal group technique (NGT) and Delphi method, we created a multidisciplinary, evidence- and consensus-based treatment guideline for JIA based on a systematic literature analysis and three consensus conferences. Conferences were headed by a professional moderator and were attended by representatives who had been nominated by their scientific societies or organizations. 15 statements regarding drug therapy, symptomatic and surgical management were generated. It is recommended that initially JIA is treated with NSAID followed by local glucocorticoids and/or methotrexate if unresponsive. Complementing literature evidence with long-standing experience of caregivers allows creating guidelines that may potentially improve the quality of care for children and adolescents with JIA. |
| Databáze: | OpenAIRE |
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