Oxidative stress/lipid peroxidation and antioxidant enzymes in apparently healthy individuals involved in physical exercise
| Autor: | Ikekpeazu Joy Ebele, Ikekpeazu Adanna Jenniger, Ogbu Innocent Sidney, Onyekwelu Kenechukwu Chibuike, Orji Oliver Chukwuma, Eze Anthonius Anayochukwu, Eke Christian Nnabugo, N Daniel |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Antioxidant medicine.medical_treatment cat lcsh:Medicine Physical exercise medicine.disease_cause Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine tas oxidative stress Aerobic exercise chemistry.chemical_classification Reactive oxygen species gpx mda business.industry Glutathione peroxidase lcsh:R 030229 sport sciences Malondialdehyde Endocrinology chemistry Immunology General Agricultural and Biological Sciences business 030217 neurology & neurosurgery Oxidative stress |
| Zdroj: | Asian Journal of Medical Sciences, Vol 7, Iss 6, Pp 16-19 (2016) |
| ISSN: | 2091-0576 2467-9100 |
| DOI: | 10.3126/ajms.v7i6.15245 |
| Popis: | Background: Normal metabolic functions generate highly reactive compounds called free radicals in the body. Exercise is accompanied by increased oxygen consumption and enhanced Reactive Oxygen Species (ROS)/free radical production in humans. These molecules react with cellular molecules such as proteins, lipids and carbohydrates, and denature them. As a result of this, vital cellular structures and functions are lost and ultimately resulting in various pathological conditions. Aims and Objective: The objective of this study was to determine the effect of physical exercise on lipid peroxidation and antioxidant enzymes in apparently healthy individuals. Materials and Methods: A total of 96 samples were collected from apparently healthy adults aged between 18 and 25 years before and after morning exercise session. The samples were analyzed for Total Antioxidant Activity (TAS), pro-oxidant biomarker- malondialdehyde (MDA) and antioxidant enzymes – catalase (CAT) and glutathione peroxidase (GPx) by spectrophotometic method. Results: The result shows that TAS after exercise was significantly higher (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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