Budgetary impact of diagnostic tests for visceral leishmaniasis in Brazil
| Autor: | Guilherme Loureiro Werneck, Tália Santana Machado de Assis, Ana Rabello, D. N. Oliveira, André Luís Ferreira de Azeredo-da-Silva, Gláucia Fernandes Cota |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Budgets
medicine.medical_specialty Time Factors National Health Programs 030231 tropical medicine Budgetary Control lcsh:Medicine Polymerase Chain Reaction Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Bone marrow aspirate Controle Orçamentário Internal medicine Direct agglutination test parasitic diseases Diagnosis medicine Humans 030212 general & internal medicine health care economics and organizations National health Visceral Leishmaniasis Indirect immunofluorescence business.industry Clinical Laboratory Techniques Diagnóstico lcsh:Public aspects of medicine lcsh:R Public Health Environmental and Occupational Health Diagnostic test Budgetary impact lcsh:RA1-1270 Direct cost medicine.disease Visceral leishmaniasis Leishmaniasis Visceral Leishmaniose Visceral Health Expenditures business Brazil |
| Zdroj: | Cadernos de Saúde Pública v.33 n.12 2017 Cadernos de Saúde Pública Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ Cadernos de Saúde Pública, Vol 33, Iss 12 (2017) |
| Popis: | The aim of the present study was to estimate the financial costs of the incorporation and/or replacement of diagnostic tests for human visceral leishmaniasis (VL) in Brazil. The analysis was conducted from the perspective of the Brazilian Unified National Health System (SUS) over a period of three years. Six diagnostic tests were evaluated: the indirect immunofluorescence antibody test (IFAT), the IT LEISH rapid test, the parasitological examination of bone marrow aspirate, the direct agglutination test (DAT-LPC) standardized in the Clinical Research Laboratory, René Rachou Institute of the Oswaldo Cruz Foundation, the Kalazar Detect rapid test, and polymerase chain reaction (PCR). The assumptions used were the number of suspected cases of VL reported to the Brazilian Ministry of Health in 2014 and the direct cost of diagnostic tests. The costs to diagnose suspected cases of VL over three years using the IFAT and the DAT-LPC were estimated at USD 280,979.91 and USD 121,371.48, respectively. The analysis indicated that compared with the use of the IFAT, the incorporation of the DAT-LPC into the SUS would result in savings of USD 159,608.43. With regard to the budgetary impact of rapid tests, the use of IT LEISH resulted in savings of USD 21.708,72 over three years. Compared with a parasitological examination, diagnosis using PCR resulted in savings of USD 3,125,068.92 over three years. In this study, the replacement of the IFAT with the DAT-LPC proved financially advantageous. In addition, the replacement of the Kalazar Detect rapid test with the IT LEISH in 2015 was economically valuable, and the replacement of parasitological examination with PCR was indicated. |
| Databáze: | OpenAIRE |
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