Effects of traditional and novel proteolytic agents on tissue dissolution and dentine microhardness

Autor: Shwetha Elizabeth Jacob, Niharika Prasad, Sreya Dutta, Vasavi Kumblekar, Srikant Natarajan, Kukkila Jayaprakash, Manuel Sebastian Thomas
Rok vydání: 2022
Předmět:
Zdroj: Australian endodontic journal : the journal of the Australian Society of Endodontology IncREFERENCES.
ISSN: 1747-4477
Popis: The study aimed to evaluate the tissue-dissolving ability of papain and bromelain with respect to that of sodium hypochlorite (NaOCl) at the temperatures of 25°C and 60°C. The study also assessed the effects of these proteolytic agents on radicular dentine microhardness. Warming NaOCl, papain and bromelain solutions resulted in significant tissue dissolution at all time intervals (p 0.001). At 60°C, bromelain showed significantly higher tissue weight loss at every time interval when compared to NaOCl (p 0.001). All of the three organic tissue dissolvents reduced the microhardness at 1 hr when compared to their respective baseline values. The reduction in microhardness from the baseline reading was statistically significant only in the papain group at 30 min (p = 0.018) and at 60 min (p = 0.03) when compared to the control group. Hence it was concluded that bromelain exerted superior tissue dissolution action, especially when warmed, with minimal effect on dentine microhardness.
Databáze: OpenAIRE