Carney complex syndrome manifesting as cardioembolic stroke: a case report and review of the literature
| Autor: | P Giannakopoulou, D.A. Kazis, S Chatzikonstantinou, C A Stratakis, C Lyssikatos, O Pikou, T Geroukis, Sevasti Bostanjopoulou, P Poulios |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Cyclic AMP-Dependent Protein Kinase RIalpha Subunit Atrial myxoma Heart Neoplasms 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Protein kinase A Carney Complex PRKAR1A Carney complex Cardioembolic stroke Embolic Stroke business.industry General Neuroscience General Medicine Syndrome medicine.disease Embolic stroke 030104 developmental biology Cardiology Lentiginosis Signal transduction business Myxoma 030217 neurology & neurosurgery |
| Zdroj: | The International journal of neuroscience. 132(7) |
| ISSN: | 1563-5279 |
| Popis: | "Carney Complex (CNC) is a familial lentiginosis syndrome, caused byWe describe a Greek family diagnosed with CNC after recurrent embolic strokes, secondary to left-sided atrial myxomas. There are limited cases in the literature describing this type of presentation for CNC; typically, most cases present with an endocrine syndrome. Our case serves as a reminder of this rare, underdiagnosed syndrome and its wide phenotypic spectrum. It is followed by a review of the current literature on cases with cerebrovascular disease as a manifestation of CNC.The co-occurrence of emboligenic cardiac myxomas and skin lesions should be an indication for screening for CNC. |
| Databáze: | OpenAIRE |
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