Plasma oxytocin and personality traits in psychiatric outpatients
| Autor: | Marie Åsberg, Maria Petersson, Jussi Jokinen, Marie Bendix, Kerstin Uvnäs-Moberg, Pär Svanborg, Petter Gustavsson |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism media_common.quotation_subject Population Anxiety Oxytocin Personality Disorders Endocrinology Sex Factors Outpatients medicine Personality Humans Big Five personality traits Psychiatry education Biological Psychiatry media_common Aged education.field_of_study Extraversion and introversion Endocrine and Autonomic Systems Middle Aged medicine.disease Personality disorders Social relation Psychiatry and Mental health Impulsive Behavior Female medicine.symptom Psychology hormones hormone substitutes and hormone antagonists Clinical psychology medicine.drug |
| Zdroj: | Psychoneuroendocrinology. 57 |
| ISSN: | 1873-3360 |
| Popis: | The oxytocin system is regarded as being of relevance for social interaction. In spite of this, very few studies have investigated the relationship between oxytocin and personality traits in clinical psychiatric populations. We assessed the relationship between personality traits and plasma oxytocin levels in a population of 101 medication-free psychiatric outpatients (men = 37, women = 64). We used the Karolinska Scale of Personality (KSP) and diagnostic and symptomatic testing. Plasma oxytocin levels were analysed with a specific radioimmunoassay at inclusion and after one month for testing of stability. Plasma oxytocin levels were stable over time and did not differ between patients with or without personality disorders, nor were they related to severity of depressive or anxiety symptoms. The KSP factors Impulsiveness and Negative Emotionality were significant independent predictors of plasma oxytocin. A subscale analysis of these personality factors showed significant positive correlations between baseline plasma oxytocin and the KSP subscales monotony avoidance and psychic anxiety. The significant association between the KSP factor Impulsiveness and oxytocin levels observed at baseline was observed also one month later in men. These findings suggest that personality traits such as Impulsiveness and Negative emotionality which are linked to social functioning in several psychiatric disorders seem to be associated with endogenous plasma oxytocin levels. These variations in oxytocin levels might have an impact on social sensitivity or social motivation with possible gender differences. |
| Databáze: | OpenAIRE |
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