Evolutionary analysis of the Moringa oleifera genome reveals a recent burst of plastid to nucleus gene duplications
Autor: | José Ojeda-López, Maria Salinas, Juan Pablo Marczuk-Rojas, Lorenzo Carretero-Paulet, Oliver Aleksandrei Polushkina, Darius Purucker |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0106 biological sciences
0301 basic medicine Nuclear gene Evolution lcsh:Medicine Genes Plant 01 natural sciences Genome Synteny Article Moringa Evolution Molecular 03 medical and health sciences chemistry.chemical_compound Gene Duplication Genetics Arabidopsis thaliana Gene family Plastids Plastid lcsh:Science Gene Phylogeny Moringa oleifera Multidisciplinary biology lcsh:R fungi food and beverages biology.organism_classification Computational biology and bioinformatics 030104 developmental biology chemistry lcsh:Q Plant sciences Sequence Alignment DNA Genome Plant 010606 plant biology & botany |
Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020) |
ISSN: | 2045-2322 |
Popis: | It is necessary to identify suitable alternative crops to ensure the nutritional demands of a growing global population. The genome of Moringa oleifera, a fast-growing drought-tolerant orphan crop with highly valuable agronomical, nutritional and pharmaceutical properties, has recently been reported. We model here gene family evolution in Moringa as compared with ten other flowering plant species. Despite the reduced number of genes in the compact Moringa genome, 101 gene families, grouping 957 genes, were found as significantly expanded. Expanded families were highly enriched for chloroplastidic and photosynthetic functions. Indeed, almost half of the genes belonging to Moringa expanded families grouped with their Arabidopsis thaliana plastid encoded orthologs. Microsynteny analysis together with modeling the distribution of synonymous substitutions rates, supported most plastid duplicated genes originated recently through a burst of simultaneous insertions of large regions of plastid DNA into the nuclear genome. These, together with abundant short insertions of plastid DNA, contributed to the occurrence of massive amounts of plastid DNA in the Moringa nuclear genome, representing 4.71%, the largest reported so far. Our study provides key genetic resources for future breeding programs and highlights the potential of plastid DNA to impact the structure and function of nuclear genes and genomes. |
Databáze: | OpenAIRE |
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