Methods of Respiratory Virus Detection: Advances towards Point-of-Care for Early Intervention
| Autor: | Liguo Liang, Shien Shen, Siming Lu, Hongrui Zhang, Sha Lin |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
2019-20 coronavirus outbreak Coronavirus disease 2019 (COVID-19) viruses Human life Viral screening detection Review 02 engineering and technology Virus 03 medical and health sciences TJ1-1570 medicine Mechanical engineering and machinery Electrical and Electronic Engineering Intensive care medicine 030304 developmental biology Point of care 0303 health sciences business.industry Mechanical Engineering COVID-19 021001 nanoscience & nanotechnology respiratory virus point-of-care Control and Systems Engineering Respiratory virus 0210 nano-technology business Viral load |
| Zdroj: | Micromachines Micromachines, Vol 12, Iss 697, p 697 (2021) |
| ISSN: | 2072-666X |
| DOI: | 10.3390/mi12060697 |
| Popis: | Respiratory viral infections threaten human life and inflict an enormous healthcare burden worldwide. Frequent monitoring of viral antibodies and viral load can effectively help to control the spread of the virus and make timely interventions. However, current methods for detecting viral load require dedicated personnel and are time-consuming. Additionally, COVID-19 detection is generally relied on an automated PCR analyzer, which is highly instrument-dependent and expensive. As such, emerging technologies in the development of respiratory viral load assays for point-of-care (POC) testing are urgently needed for viral screening. Recent advances in loop-mediated isothermal amplification (LAMP), biosensors, nanotechnology-based paper strips and microfluidics offer new strategies to develop a rapid, low-cost, and user-friendly respiratory viral monitoring platform. In this review, we summarized the traditional methods in respiratory virus detection and present the state-of-art technologies in the monitoring of respiratory virus at POC. |
| Databáze: | OpenAIRE |
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