Preparation and characterization of collagen-elastin matrices from blood vessels intended as small diameter vascular grafts
| Autor: | Selma Raymundo, Gilberto Goissis, Domingo Marcolino Braile, José Vitor Maniglia, Diderot Rodrigues Parreira, S Suzigan |
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| Rok vydání: | 2000 |
| Předmět: |
Small diameter
Vena Cava Superior Cell Biomedical Engineering Medicine (miscellaneous) Bioengineering Biocompatible Materials Vena Cava Inferior Alkalies Iliac Vein Prosthesis Design Iliac Artery Biomaterials Matrix (mathematics) Dogs Thoracic Arteries medicine Animals Denaturation (biochemistry) Dimethyl Sulfoxide Aorta Abdominal Large diameter Coloring Agents Bioprosthesis biology Calorimetry Differential Scanning Chemistry General Medicine Femoral Vein Blood Vessel Prosthesis Elastin Electrophysiology Femoral Artery medicine.anatomical_structure Cross-Linking Reagents cardiovascular system biology.protein Microscopy Electron Scanning Solvents Blood Vessels Collagen Tissue Preservation Elastic fiber Blood vessel Biomedical engineering |
| Zdroj: | Artificial organs. 24(3) |
| ISSN: | 0160-564X |
| Popis: | This study describes the selective removal of cell and cell residues from small and large diameter blood vessels for the preparation of tubular collagen:elastin matrices intended for small diameter vascular prosthesis. The results showed that total or partially devitalized collagen:elastin matrices may be conveniently prepared without denaturation of the collagen:elastin matrix with a high degree of preservation of the proteins. The efficiency of cell removal and the extent collagen and elastic fiber preservation were dependent on the segment and the type of blood vessel under study, with arteries characterized by a higher susceptibility of cell removal and better preservation of the collagen-elastin matrix. |
| Databáze: | OpenAIRE |
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