Arrhythmia Risk Prediction in Idiopathic Dilated Cardiomyopathy Based on Heart Rate Variability and Baroreflex Sensitivity
| Autor: | Wolfram Grimm, Bernhard Maisch, Michael Christ, Julia Sharkova |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Cardiomyopathy
Dilated Male medicine.medical_specialty Baroreflex Sudden death Heart Rate Predictive Value of Tests Risk Factors Internal medicine Idiopathic dilated cardiomyopathy Humans Medicine Heart rate variability Sustained VT Sinus rhythm Phenylephrine Ejection fraction business.industry Arrhythmias Cardiac General Medicine Middle Aged Anesthesia Cardiology Female Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology medicine.drug |
| Zdroj: | Pacing and Clinical Electrophysiology. 28:S202-S206 |
| ISSN: | 1540-8159 0147-8389 |
| Popis: | UNLABELLED This study examined the relation between heart rate variability (HRV) and baroreflex sensitivity (BRS) and subsequent major arrhythmic events (MAE), defined as sustained VT, VF or sudden death, in 263 patients with idiopathic dilated cardiomyopathy (IDC) in sinus rhythm. The predefined measure of HRV was the standard deviation of all normal-to-normal RR intervals (SDNN) on baseline 24-hour ambulatory ECG. BRS was determined by the phenylephrine method. Over 52 +/- 21 months of follow-up, MAE occurred in 38 patients (14%). SDNN at baseline 24-hour ambulatory ECG (106 +/- 46 vs 109 +/- 45, ns) and BRS (7.9 +/- 5.5 vs 7.7 +/- 5.3 ms/mmHg, ns) were both similar in patients with versus without MAE during follow-up. In contrast, left ventricular ejection fraction was significantly lower in patients with versus without MAE (24%+/- 7% vs 31%+/- 10%, P < 0.019. CONCLUSIONS Neither HRV nor BRS predicted MAE in patients with IDC. |
| Databáze: | OpenAIRE |
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