Cutaneous mast cell tumors in 11 miniature pigs: a retrospective study
Autor: | Brittany L. Rasche, Kristie Mozzachio, Keith E. Linder |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | J Vet Diagn Invest |
ISSN: | 1943-4936 1040-6387 |
Popis: | Better understanding of mast cell tumors (MCTs) in miniature pigs is needed to guide diagnosis and establish clinical significance. We characterized the gross pathology, histopathology, histochemical staining, and KIT immunoreactivity of cutaneous MCTs in a retrospective descriptive study of 11 miniature pigs ( Sus scrofa domesticus). Tumors were single or multiple papules, small nodules, or plaques. In one pig, lymph nodes and internal organs were affected. Histologically, all MCTs involved the dermis, and some extended to the subcutis (4 of 11) and skeletal muscle (1 of 11). Most tumors were well-demarcated, unencapsulated, nodular or multinodular masses (8 of 11) and fewer were poorly demarcated plaques (3 of 11). Neoplastic cells were often well-differentiated with pale amphophilic-to-eosinophilic faintly granular cytoplasm, occasional binucleation, rare multinucleation, and a low mitotic count ( |
Databáze: | OpenAIRE |
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