Cutaneous mast cell tumors in 11 miniature pigs: a retrospective study

Autor:	Brittany L. Rasche, Kristie Mozzachio, Keith E. Linder
Rok vydání:	2022
Předmět:	Swine Diseases Mastocytoma Skin Proto-Oncogene Proteins c-kit Skin Neoplasms General Veterinary Swine Animals Swine Miniature Brief Reports Mast Cells Tolonium Chloride Retrospective Studies
Zdroj:	J Vet Diagn Invest
ISSN:	1943-4936 1040-6387
Popis:	Better understanding of mast cell tumors (MCTs) in miniature pigs is needed to guide diagnosis and establish clinical significance. We characterized the gross pathology, histopathology, histochemical staining, and KIT immunoreactivity of cutaneous MCTs in a retrospective descriptive study of 11 miniature pigs ( Sus scrofa domesticus). Tumors were single or multiple papules, small nodules, or plaques. In one pig, lymph nodes and internal organs were affected. Histologically, all MCTs involved the dermis, and some extended to the subcutis (4 of 11) and skeletal muscle (1 of 11). Most tumors were well-demarcated, unencapsulated, nodular or multinodular masses (8 of 11) and fewer were poorly demarcated plaques (3 of 11). Neoplastic cells were often well-differentiated with pale amphophilic-to-eosinophilic faintly granular cytoplasm, occasional binucleation, rare multinucleation, and a low mitotic count (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034213034cae1a93d258a3f57ad0e149 https://doi.org/10.1177/10406387221079255 Zobrazit plný text záznamu