Nasopharyngeal colonization of otopathogens in South Indian children with acute otitis media - A case control pilot study
| Autor: | P. Naina, V. Rosemol, V. Balaji, M. Napolean, Ajoy Mathew Varghese, J. Periyasamy, Mary John |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Staphylococcus aureus Microbiological culture Population Case control study Acute otitis media medicine.disease_cause Moraxella catarrhalis 03 medical and health sciences 0302 clinical medicine Internal medicine Streptococcus pneumoniae otorhinolaryngologic diseases Medicine Risk factor 030223 otorhinolaryngology education education.field_of_study biology business.industry Case-control study biology.organism_classification Haemophilus influenzae Carriage Otorhinolaryngology RF1-547 Quellung reaction Otopathogens business 030217 neurology & neurosurgery Nasopharyngeal Research Article |
| Zdroj: | Journal of Otology Journal of Otology, Vol 16, Iss 4, Pp 220-224 (2021) |
| ISSN: | 2524-1753 |
| Popis: | Background: Acute otitis media (AOM) is an inflammatory disease of the middle ear causing significant morbidity in early childhood. A pilot study was undertaken to identify the role of various risk factors South Indian children with AOM, especially the role of nasopharyngeal otopathogens. Methodology: A prospective case control pilot study was conducted in children aged below six years, presenting to a single tertiary care from 2018 to 2019. Fifty cases with AOM and 45 age and gender matched controls were recruited. Two nasopharyngeal swabs were collected, one was processed for bacterial culture. The other swab was processed according to the CDC recommended broth enrichment method to identify carriage of S. pneumoniae. Subsequent serotyping was done by Quellung method and conventional sequential multiplex PCR. Result: Otalgia was the major presentation seen in 92% of the children with AOM. None of the clinical and demographic characteristics were found to be statistically significant between the cases and controls. The most common otopathogen was S. pneumoniae (55%) followed by H. influenza (29%). The common S. pneumoniae serotypes encountered were 11A and 19F.Nasopharyngeal colonization with S. pneumoniae [OR 6.57, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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