Pulmonary Rehabilitation in Noncystic Fibrosis Bronchiectasis
| Autor: | Josuel Ora, Beatrice Ludovica Ritondo, Paola Rogliani, Xhesika Pata, Emanuela Prendi, Florian Spada |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Bronchiectasis business.industry medicine.medical_treatment medicine.disease Incremental Shuttle Walk Test Noncystic fibrosis bronchiectasis Pulmonary function testing Pulmonary rehabilitation Incremental shuttle walk test Exercise tolerance Fibrosis Walk test Statistical significance Internal medicine Settore MED/10 medicine Respiratory function 6-Min walk test business |
| Zdroj: | Respiration. 101:97-105 |
| ISSN: | 1423-0356 0025-7931 |
| DOI: | 10.1159/000517527 |
| Popis: | Background: Current guidelines for the treatment of noncystic fibrosis bronchiectasis (NCFB) recommend pulmonary rehabilitation (PR), but to date, there are few studies that have proven its effectiveness. Objective: The main objective of this study was to examine the effect of PR on pulmonary function tests and exercise capacity. Method: The aim of this study was to systematically review the effects of PR in NCFB on (1) forced expiratory volume in the first second (FEV1) and (2) exercise capacity evaluated by the 6-min walk test (6MWT) and the incremental shuttle walk test (ISWT). This meta-analysis was undertaken according to PRISMA recommendations. Results: This pair-wise meta-analysis included data obtained from studies that enrolled 529 NCFB patients. The FEV1 assessment after PR between the active and control group did not show any significant increase (FEV1 difference 0.084 mL; CI: −0.064, +0.233; p = 0.264), and there was an increasing trend (188 mL; CI: −0 to 0.009, +0.384) at the limits of statistical significance (p = 0.061). Walked distance showed a significant increase in the PR group compared to the control group (ISWT distance difference 070.0 m; CI: 55.2, 84.8; p < 0.001), and this finding was confirmed before and after PR both by the ISWT (68.85 m greater than baseline; CI: 40.52, 97.18; p < 0.001) and by the 6MWT (37.7 m greater than baseline; CI: 20.22, 55.25; p < 0.001). Conclusions: PR improves exercise tolerance in NCFB patients, but it has a modest impact on respiratory function. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|