Maternal and neonatal infections of herpes simplex virus-1 and cytomegalovirus in Saudi Arabia

Autor: Ahmed S. Abdel-Moneim, Raad M.M. Althaqafi, Mohamed Elrewiny
Rok vydání: 2019
Předmět:
0301 basic medicine
Human cytomegalovirus
Infertility
viruses
Herpesvirus 2
Human

030106 microbiology
Congenital cytomegalovirus infection
Saudi Arabia
Intrauterine growth restriction
Cytomegalovirus
Herpesvirus 1
Human

Abortion
medicine.disease_cause
Antibodies
Viral

Infant
Newborn
Diseases

lcsh:Infectious and parasitic diseases
03 medical and health sciences
0302 clinical medicine
Pregnancy
medicine
Humans
lcsh:RC109-216
030212 general & internal medicine
Pregnancy Complications
Infectious

Fetal Growth Retardation
business.industry
Incidence (epidemiology)
lcsh:Public aspects of medicine
Public Health
Environmental and Occupational Health

Infant
Newborn

lcsh:RA1-1270
Herpes Simplex
General Medicine
medicine.disease
Infectious Disease Transmission
Vertical

Infectious Diseases
Herpes simplex virus
Immunoglobulin M
Immunoglobulin G
Immunology
Cytomegalovirus Infections
Female
business
Zdroj: Journal of Infection and Public Health, Vol 13, Iss 2, Pp 313-314 (2020)
ISSN: 1876-035X
Popis: It is common practice to screen for human cytomegalovirus (CMV) and herpes simplex virus (HSV) among women with infertility problems, recurrent abortion or exhibiting intrauterine growth restriction during pregnancy. Nonetheless, limited information exists about the incidence of these viruses in Saudi Arabia. The IgG and IgM antibodies of 761 women and 85 of neonates who showed intrauterine growth retardation (IUGR) were reviewed against cytomegalovirus and herpes simplex virus-1. Tests were repeated only for those with positive results. Recent infection of herpes simplex virus-1 and cytomegalovirus was evidenced by the presence of IgM in the female patients: incidence was 1.1% and 1.3% respectively. None of the neonates showed positive IgM for cytomegalovirus, but a single case showed a positive result for herpes simplex virus-1 IgM. Among the female patients, however, the presence of IgG indicated previous exposure to cytomegalovirus in 92% of cases and herpes simplex virus in 80.8%. It was concluded that although previous exposure to CMV and HSV-1 were found in high percentages in women experiencing infertility problems but did not appear to be associated with neonates exhibiting intrauterine growth retardation. Keywords: Abortion, CMV, HSV, Infertility problems, Intrauterine growth retardation
Databáze: OpenAIRE