Dissociation of minor satellite from the centromere in mouse

Autor:	B.K. Vig, Jennifer Frankovich, D. Latour
Rok vydání:	1994
Předmět:	Satellite DNA Centromere Fluorescent Antibody Technique Cell Biology DNA Satellite Biology Molecular biology Cell Line Chromosome Banding Mice Bisbenzimidazole chemistry.chemical_compound chemistry Animals Kinetochores In Situ Hybridization DNA Satellite chromosome
Zdroj:	Journal of Cell Science. 107:3091-3095
ISSN:	1477-9137 0021-9533
DOI:	10.1242/jcs.107.11.3091
Popis:	The minor satellite DNA of mouse is believed to constitute the centromere. We report that centromeres of some chromosomes in the Cl1D cells of mouse are not associated with this DNA even though the latter is present on these chromosomes. The satellite DNA was detected distally from the centromere and could not be mistaken as a component of the centromere. We also report that the site of the primary constriction may not always coincide with the site of the anti-kinetochore antibody reaction. Whereas the regions containing the major satellite decondense upon treatment with bisbenzimidazole (Hoechst 33258), the sites carrying minor satellite resist decondensing.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033415fe8e874a1e5a8da8ccfd00137a https://doi.org/10.1242/jcs.107.11.3091 Zobrazit plný text záznamu