T-category reflects the histopathologic characteristics of gallbladder cancer
| Autor: | Eun Kyung Hong, Sang Myung Woo, Sung Yong Cho, Sung Sik Han, Sung Heon Kim, Woojin Lee, Tae Hyun Kim, Sun Jin Park, Yongsun Kim |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Neoplasm Residual medicine.medical_treatment Kaplan-Meier Estimate Severity of Illness Index Risk Factors Republic of Korea Biomarkers Tumor Humans Medicine Cholecystectomy Neoplasm Invasiveness Gallbladder cancer Aged Neoplasm Staging Retrospective Studies Analysis of Variance business.industry Gallbladder Hazard ratio Cancer Retrospective cohort study General Medicine Middle Aged Prognosis medicine.disease Primary tumor medicine.anatomical_structure Oncology Chemotherapy Adjuvant Lymphatic Metastasis Multivariate Analysis Female Gallbladder Neoplasms Surgery CA19-9 Radiology business |
| Zdroj: | European Journal of Surgical Oncology (EJSO). 38:537-542 |
| ISSN: | 0748-7983 |
| Popis: | Gallbladder (GB) cancer is a relatively uncommon gastrointestinal malignancy and is known to often result in unfavorable outcomes. Recent advances in aggressive surgical resection have improved the overall survival rate of patients with GB cancer. We aimed to evaluate the outcomes and prognostic factors of GB cancer following a surgical resection with curative intent.Between March 2001 and March 2009, 89 patients with GB cancer underwent surgical resection with curative intent at the National Cancer Center of Korea. We then conducted a retrospective analysis of clinicopathologic data.Nineteen patients underwent simple cholecystectomy and 70 patients underwent extended cholecystectomy. Tumor-free resection margins were obtained in 84 cases. The 1-, 3- and 5-year disease-specific survival rates in the 89 patients were 85.8%, 68.0% and 64.1%, respectively. By multivariate analysis, only the T-category was significant (p0.001). The T-category showed a close correlation with all of the other histopathologic factors which were significant in univariate analysis.The T-category of GB cancer represents not only the depth of the primary tumor but also the aggressiveness of its histopathologic nature. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect