Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment

Autor: Naoki Sakane, Yuko Kurosawa, Takafumi Hamaoka, Sawako Wakui, Shinsuke Nirengi, Toshiyuki Homma, Shiho Amagasa
Rok vydání: 2018
Předmět:
Zdroj: Journal of Physiological Anthropology
Journal of Physiological Anthropology, Vol 37, Iss 1, Pp 1-7 (2018)
ISSN: 1880-6805
Popis: Background Brown adipose tissue (BAT) is sympathetically activated and induces thermogenesis during cold exposure, thereby influencing energy expenditure and body fat levels. The very low frequency (VLF) components of pulse rate variability could be a form of thermogenic sympathetic nervous activity, but no clear relationship has yet been reported between VLF activity and BAT density. We therefore aimed to evaluate the association between them. Methods We enrolled 20 adults in winter and 20 matched adults in summer. We assessed BAT densities based on total hemoglobin concentrations ([total-Hb]) measured with near-infrared time-resolved spectroscopy. We calculated VLF activity from pulse rate variability measurements. Results BAT density ([total-Hb]; winter 70.5 ± 17.0 μM, summer 57.8 ± 18.3 μM) and VLF activity (winter 6.7 ± 0.8, summer 6.1 ± 0.9) were significantly higher in winter than in summer (P
Databáze: OpenAIRE