Infection Rates of Electrical Leads Used for Percutaneous Neurostimulation of the Peripheral Nervous System
Autor: | John Chae, Michael C. Donohue, Michael Saulino, Joseph W. Boggs, Amorn Wongsarnpigoon, P. Hunter Peckham, Rodney A. Gabriel, Matthew G. deBock, Brian M. Ilfeld, Christopher A. Gilmore, Stuart A. Grant |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Percutaneous medicine.medical_treatment Medical Physiology Clinical Sciences percutaneous peripheral nerve stimulation Electric Stimulation Therapy Lower risk Article 03 medical and health sciences 0302 clinical medicine Anesthesiology 030202 anesthesiology small-diameter open-coiled helical lead Peripheral Nervous System medicine Clinical endpoint Humans Pain Management Lead (electronics) Neurostimulation Retrospective Studies Plexus business.industry helical lead Neurosciences Retrospective cohort study Surgery Anesthesiology and Pain Medicine medicine.anatomical_structure Needles Peripheral nervous system Anesthesia neuromodulation Equipment Contamination Analgesia business peripheral nerve stimulator postoperative pain 030217 neurology & neurosurgery |
Zdroj: | Ilfeld, BM; Gabriel, RA; Saulino, MF; Chae, J; Peckham, PH; Grant, SA; et al.(2017). Infection Rates of Electrical Leads Used for Percutaneous Neurostimulation of the Peripheral Nervous System. PAIN PRACTICE, 17(6), 753-762. doi: 10.1111/papr.12523. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/8wc3x653 Pain practice : the official journal of World Institute of Pain, vol 17, iss 6 |
DOI: | 10.1111/papr.12523. |
Popis: | Author(s): Ilfeld, Brian M; Gabriel, Rodney A; Saulino, Michael F; Chae, John; Peckham, P Hunter; Grant, Stuart A; Gilmore, Christopher A; Donohue, Michael C; deBock, Matthew G; Wongsarnpigoon, Amorn; Boggs, Joseph W | Abstract: BackgroundPercutaneous neurostimulation of the peripheral nervous system involves the insertion of a wire "lead" through an introducing needle to target a nerve/plexus or a motor point within a muscle. Electrical current may then be passed from an external generator through the skin via the lead for various therapeutic goals, including providing analgesia. With extended use of percutaneous leads sometimes greater than a month, infection is a concern. It was hypothesized that the infection rate of leads with a coiled design is lower than for leads with a noncoiled cylindrical design.MethodsThe literature was retrospectively reviewed for clinical studies of percutaneous neurostimulation of the peripheral nervous system of greater than 2 days that included explicit information on adverse events. The primary endpoint was the number of infections per 1,000 indwelling days.ResultsForty-three studies were identified that met inclusion criteria involving coiled (n = 21) and noncoiled (n = 25) leads (3 studies involved both). The risk of infection with noncoiled leads was estimated to be 25 times greater than with coiled leads (95% confidence interval [CI] 2 to 407, P = 0.006). The infection rates were estimated to be 0.03 (95% CI 0.01 to 0.13) infections per 1,000 indwelling days for coiled leads and 0.83 (95% CI 0.16 to 4.33) infections per 1,000 indwelling days for noncoiled leads (P = 0.006).ConclusionsPercutaneous leads used for neurostimulation of the peripheral nervous system have a much lower risk of infection with a coiled design compared with noncoiled leads: approximately 1 infection for every 30,000 vs. 1,200 indwelling days, respectively. |
Databáze: | OpenAIRE |
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