First documented outbreak of KPC-2-producing Klebsiella pneumoniae in Switzerland: infection control measures and clinical management

Autor: T. Bruderer, Matthias Schlegel, G.-R. Kleger, Daniel Goldenberger, Eva Lemmenmeier, Philipp Kohler
Přispěvatelé: University of Zurich, Lemmenmeier, E
Rok vydání: 2013
Předmět:
Male
Klebsiella pneumoniae
Minocycline
Tigecycline
2726 Microbiology (medical)
Disease Outbreaks
10234 Clinic for Infectious Diseases
Tertiary Care Centers
Epidemiology
polycyclic compounds
Infection control
biology
General Medicine
Middle Aged
Anti-Bacterial Agents
Electrophoresis
Gel
Pulsed-Field
Intensive Care Units
Infectious Diseases
Treatment Outcome
KPC-2 producing Klebsiella pneumoniae
Switzerland
medicine.drug
Microbiology (medical)
Adult
medicine.medical_specialty
Genotype
610 Medicine & health
Meropenem
beta-Lactamases
Internal medicine
medicine
Humans
Intensive care medicine
Aged
Infection Control
business.industry
Colistin
Outbreak
2725 Infectious Diseases
biochemical phenomena
metabolism
and nutrition
bacterial infections and mycoses
biology.organism_classification
Klebsiella Infections
Molecular Typing
Thienamycins
business
Zdroj: Europe PubMed Central
ISSN: 1439-0973
Popis: We report the epidemiological and clinical features of the first outbreak of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-KP) type 2 in Switzerland. The outbreak took place in the medical intensive care unit (MICU) of our tertiary care hospital and affected three severely ill patients. After the implementation of strict infection control measures, no further patients colonised with KPC-KP could be detected by the screening of exposed patients. Successful treatment of patients infected with KPC-KP consisted of a combination therapy of meropenem, colistin and tigecycline.
Databáze: OpenAIRE
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