Pulmonary function and high-resolution computed tomography in outdoor rock drillers exposed to crystalline silica
| Autor: | May Brit Lund, Trond Mogens Aaløkken, Nils Petter Skaugset, Dag G. Ellingsen, Thomas Clemm, Mariann Ulvestad, Anne Günther, Bente Ulvestad |
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| Rok vydání: | 2019 |
| Předmět: |
Spirometry
Adult Male High-resolution computed tomography Vital capacity Pulmonary Fibrosis Silicosis Pulmonary disease Cumulative Exposure Airflow obstruction Pulmonary function testing 03 medical and health sciences 0302 clinical medicine Occupational Exposure medicine Humans 030212 general & internal medicine Lung Diseases Obstructive Aged Smokers medicine.diagnostic_test business.industry Norway Construction Industry Public Health Environmental and Occupational Health Middle Aged medicine.disease Silicon Dioxide 030210 environmental & occupational health Respiratory Function Tests Particulate Matter Nuclear medicine business Tomography X-Ray Computed |
| Zdroj: | Occupational and environmental medicine. 77(9) |
| ISSN: | 1470-7926 |
| Popis: | ObjectivesChronic obstructive pulmonary disease and silicosis are associated with exposure to crystalline silica. We determined the exposure to respirable crystalline silica and estimated exposure–response relationships between cumulative exposure and pulmonary function in outdoor rock drillers.Methods136 rock drillers and 48 referents were recruited from three heavy construction companies. 98 air samples were collected by personal sampling for determination of respirable particulate matter and crystalline silica. Information about individual job tasks, type of drilling equipment and years of exposure in different job categories was obtained by interview. Cumulative exposure to crystalline silica was calculated for all workers. Pulmonary function was assessed by spirometry. A subgroup of 39 subjects with high cumulative exposure to crystalline silica underwent high-resolution computed tomography (HRCT).ResultsCumulative exposure (mean (min–max)) to crystalline silica was 0.69 mg٠years m–3 (0.01–5.89) in the exposed group. Mean time of exposure among rock drillers was 10.7 years (1–42). Compared with referents, the rock drillers had a lower forced expiratory volume in one second/forced vital capacity ratio (79.4 vs 81.4, p–3/years. Silicosis was not detected in HRCT, but other patterns of fibrosis and emphysema were seen.ConclusionsOutdoor rock drillers exposed to crystalline silica had significantly lower pulmonary function than referents, and signs of airflow obstruction. Silicosis was not detected. |
| Databáze: | OpenAIRE |
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