Determinants of Adrenal Androgen Hypofunction in Premenopausal Females With Rheumatoid Arthritis

Autor:	J. Rovensky, Miroslav Vlcek, Z. Radikova, Richard Imrich, J. Kerlik, Adela Penesova, J. Lukac, M. Vogeser, F. Kirchhoff
Rok vydání:	2014
Předmět:	Adult medicine.medical_specialty Physiology medicine.drug_class Arthritis Dehydroepiandrosterone Context (language use) Adrenocorticotropic hormone Severity of Illness Index Arthritis Rheumatoid Adrenocorticotropic Hormone Adrenal Cortex Hormones Prednisone Internal medicine 11-beta-Hydroxysteroid Dehydrogenase Type 1 Humans Medicine Androstenedione business.industry 17-alpha-Hydroxyprogesterone General Medicine medicine.disease Androgen Endocrinology Adipose Tissue Premenopause Case-Control Studies Adrenal Cortex Androgens Female business hormones hormone substitutes and hormone antagonists Glucocorticoid medicine.drug
Zdroj:	Physiological Research. :321-329
ISSN:	1802-9973 0862-8408
DOI:	10.33549/physiolres.932663
Popis:	The aim of our study was to investigate adrenocortical function in the context of disease activity and inflammatory status in premenopausal RA females. Adrenal glucocorticoid and androgen responses to the 1 µg ACTH 1-24 test were investigated in 23 premenopausal RA and in 15 age- and BMI-matched healthy females. Twelve RA patients were on low-dose prednisone (3.2 had lower (p3.2 had lower (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031c666a210d60088127b2693dff1923 https://doi.org/10.33549/physiolres.932663 Zobrazit plný text záznamu