Oral desensitization to milk: how to choose the starting dose!
| Autor: | Maurizio de Martino, Maria Elisabetta Rossi, Elio Novembre, Neri Pucci, Chiara Azzari, Francesca Mori |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Allergy Pediatrics medicine.medical_specialty Adolescent medicine.medical_treatment Immunology Short Communications Dose-Response Relationship Immunologic Administration Oral Milk allergy children food allergy Food allergy medicine Hypersensitivity Immunology and Allergy Animals Humans Child Desensitization (medicine) End point business.industry Test procedures end point skin prick test Immunoglobulin E medicine.disease milk allergy Surgery Skin Test End-Point Titration Milk Desensitization Immunologic Milk hypersensitivity Child Preschool Pediatrics Perinatology and Child Health Female oral desensitization Milk Hypersensitivity business |
| Zdroj: | Pediatric Allergy and Immunology |
| ISSN: | 1399-3038 0905-6157 |
| Popis: | Mori F, Pucci N, Rossi ME, de Martino M, Azzari C, Novembre E. Oral desensitization to milk: how to choose the starting dose! Pediatr Allergy Immunol 2010: 21: e450–e453. © 2009 John Wiley & Sons A/S A renewed interest in oral desensitization as treatment for food allergy has been observed in the last few years. We studied a novel method based on the end point skin prick test procedure to establish the starting dose for oral desensitization in a group of 30 children higly allergic to milk. The results (in terms of reactions to the first dose administered) were compared with a group of 20 children allergic to milk as well. Such control group started to swallow the same dose of 0.015 mg/ml of milk. None reacted to the first dose when administered according to the end point skin prick test. On the other side, ten out of 20 children (50%) from the control group showed mild allergic reactions to the first dose of milk. In conclusion the end point skin prick test procedure results safe and easy to be performed in each single child in order to find out the starting dose for oral desensitization to milk, also by taking into account the individual variability. |
| Databáze: | OpenAIRE |
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