Icb-1Gene Expression is Elevated in Human Endometrial Adenocarcinoma and is Closely Associated With HER2 Expression

Autor:	Claus Lattrich, Maciej Skrzypczak, Anette Springwald, Oliver Treeck, Olaf Ortmann, Regina Goerse
Rok vydání:	2010
Předmět:	Cancer Research medicine.medical_specialty Receptor ErbB-2 Adenocarcinoma Biology Endometrial tissue Andrology Endometrium Internal medicine Gene expression medicine Humans Neoplasm Invasiveness Gene Aged Aged 80 and over Endometrial adenocarcinoma Her2 expression Reverse Transcriptase Polymerase Chain Reaction Endometrial cancer Intracellular Signaling Peptides and Proteins General Medicine Middle Aged Normal endometrium medicine.disease Endometrial Neoplasms Neoplasm Proteins Up-Regulation Gene Expression Regulation Neoplastic Endocrinology Oncology Significant positive correlation Female
Zdroj:	Cancer Investigation. 28:904-909
ISSN:	1532-4192 0735-7907
DOI:	10.3109/07357907.2010.483511
Popis:	Human gene icb-1 (C1orf38) has been initially cloned by our group from endometrial adenocarcinoma cells. In this study, we examined icb-1 expression in 90 endometrial cancer and normal endometrial tissue specimens. Expression of icb-1 was significantly (about 3.5-fold) higher in endometrial cancer than in normal endometrium (p
Databáze:	OpenAIRE
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