IgG4-related disease of the paratestis with the scrotal fluid: A case report
| Autor: | Kunio Mochizuki, Tetsuo Kondo, Ippei Tahara, Naoko Mochizuki, Kazuki Kasai, Yuki Hanai, Shiori Murata, Kumiko Nakazawa |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pathology medicine.medical_specialty Histology T cell Biopsy Immunocytochemistry Plasma Cells 030209 endocrinology & metabolism Salivary Glands Pathology and Forensic Medicine Autoimmune Diseases 03 medical and health sciences 0302 clinical medicine Cytology parasitic diseases medicine Humans Aged CD20 Salivary gland biology business.industry fungi General Medicine medicine.disease Immunohistochemistry medicine.anatomical_structure 030220 oncology & carcinogenesis Immunoglobulin G biology.protein IgG4-related disease Immunoglobulin G4-Related Disease Pancreas business |
| Zdroj: | Diagnostic cytopathology. 47(2) |
| ISSN: | 1097-0339 |
| Popis: | IgG4-related disease (IgG4-RD) can affect various organs, and the pancreas and salivary gland are representative examples. We report a rare case of IgG4-RD of the paratestis. A 74-year-old man presented with left scrotal swelling. Scrotopuncture drainage and cytology confirmed a clear, yellow retention liquid (130 mL) with many small, similar lymphocytes and a few plasmacytes. Many lymphoid cells were immunopositive for CD3 on a cell block section, indicating that a predominant type of lymphoid cells was T cell. There were also some CD20 immunopositive cells and a few IgG4 immunopositive cells. Two months later the left scrotal swelling had returned, and he underwent radical inguinal orchiectomy. Microscopically, there was considerable lymphoplasmacytic inflammatory infiltration, fibrosis and abundant IgG4 immunopositive cells in the paratesticular region. The histopathologic and immunohistochemistry findings were consistent with IgG4-RD. However, the abundant T cells in the scrotal fluid complicated the cytological diagnosis in our case. |
| Databáze: | OpenAIRE |
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