Misdirected aqueous flow in rhegmatogenous retinal detachment: a pathophysiology update
| Autor: | James Scott Schutz, Florence Hoogewoud, Nikolaos Mavrakanas, David Tabibian |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
genetic structures Vitreous Detachment Posterior vitreous detachment Aqueous Humor Ophthalmology medicine Humans Subretinal Fluid/physiology Retina Aqueous flow business.industry Subretinal Fluid Retinal Detachment Retinal Detachment/physiopathology Retinal detachment Aqueous Humor/physiology medicine.disease Retinal Perforations Aqueous misdirection Pathophysiology eye diseases ddc:616.8 Retinal Tear Vitreous Body Vitreous Detachment/physiopathology medicine.anatomical_structure Vitreoretinal traction sense organs Retinal Perforations/physiopathology business Vitreous Body/pathology |
| Zdroj: | Survey of Ophthalmology, Vol. 60, No 1 (2015) pp. 51-59 |
| ISSN: | 0039-6257 |
| Popis: | It is widely accepted that the origin of subretinal fluid in rhegmatogenous retinal detachment (RRD) is liquid vitreous and that posterior vitreous detachment (PVD) and associated retinal tears are caused by vitreoretinal traction from intra-ocular currents, contraction of collagen fibers, and gravity. These explanations, however, are incomplete. We present a new synthesis of experimental and clinical evidence, updating understanding of fundamental pathophysiological processes in RRD. Misdirected aqueous flow is shown to more convincingly explain the origin of subretinal fluid in clinical RRD, to be the most likely cause of acute PVD and retinal tear formation, and also to contribute to initial detachment of the retina at retinal tears. Misdirected aqueous flow in RRD is a pathophysiological process, rather than the "aqueous misdirection syndrome", and occurs without visible anterior chamber shallowing or acute glaucoma. |
| Databáze: | OpenAIRE |
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