Ischemic nephropaty: The role of the renal artery stenosis revascularization on renal stem cells
| Autor: | Silvia Lai, Mariadelina Simeoni, Federica Errigo, Rosario Cianci, Adolfo Perrotta, Sandro Mazzaferro, Eleonora Cianci, Claudio Ferri, Antonietta Gigante |
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| Přispěvatelé: | Cianci, R., Perrotta, A. M., Gigante, A., Errigo, F., Ferri, C., Cianci, E., Simeoni, M., Mazzaferro, S., Lai, S. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Medicine (General) medicine.medical_specialty Percutaneous medicine.medical_treatment Case Report Renal revascularization Revascularization Renal artery stenosis urologic and male genital diseases Kidney Renal Artery Obstruction Staminal renal cell Renovascular hypertension R5-920 Stem Cell Internal medicine medicine Percutaneous transluminal renal angioplasty Stent Renal artery stenosi staminal renal cells Renal stem cell Aged renal artery stenosis Proteinuria business.industry Angioplasty General Medicine Color doppler ultrasound medicine.disease Blood pressure Hypertension Renovascular Cardiology medicine.symptom business Human |
| Zdroj: | Medicina, Vol 57, Iss 944, p 944 (2021) Medicina |
| Popis: | We report the case of a 65-year-old man with acute GFR decline to 37 mL/min and uncontrolled high blood pressure. He was suspected for renovascular hypertension and underwent a renal color Doppler ultrasound scan that detected a bilateral atherosclerotic renal artery stenosis. A digital selective angiography by percutaneous transluminal angioplasty and stenting (PTRAs) was successfully performed. Blood pressure rapidly normalized, GFR increased within a few days, and proteinuria disappeared thereafter. These clinical goals were accompanied by a significant increase of circulating renal stem cells (RSC) and a slight increase of resistive index (RI) in both kidneys. This single observation suggests the need for extensive studies aimed at evaluating the predictive power of RI and RSC in detecting post-ischemic renal repair mechanisms. |
| Databáze: | OpenAIRE |
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