Highly effective and diastereoselective synthesis of axially chiral bis-sulfoxide ligands via oxidative aryl coupling
| Autor: | Yong-Gui Zhou, Xiang Dong, Duo-Sheng Wang, Qing-An Chen, Yuxue Li, Chen Muwang |
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| Rok vydání: | 2010 |
| Předmět: |
inorganic chemicals
Stereochemistry organic chemicals Aryl Organic Chemistry Sulfoxide Oxidative phosphorylation Biochemistry Coupling (electronics) chemistry.chemical_compound chemistry Axial chirality Allyltrichlorosilane health occupations polycyclic compounds heterocyclic compounds Oxidative coupling of methane Physical and Theoretical Chemistry Axial symmetry |
| Zdroj: | Organic letters. 12(9) |
| ISSN: | 1523-7052 |
| Popis: | A series of axially chiral bis-sulfoxide ligands have been efficiently synthesized via oxidative coupling with high diastereoselectivities. The axial chirality is well controlled by the tert-butylsulfinyl or the p-tolylsulfinyl group. These axially chiral bis-sulfoxides proved to be remarkably efficient ligands for the rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to 2-cyclohexenone with 99% ee. |
| Databáze: | OpenAIRE |
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