Supplementary Figures 1 - 4 from Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Autor: Nathanael S. Gray, David M. Sabatini, Kwok-Kin Wong, Pasi A. Janne, Stephen J. Elledge, Danny M. Chou, Kathryn D. Held, Hidemasa Kawamura, Abigail Altabef, Tanya Tupper, Yuchuan Wang, Matthew P. Patricelli, Seong A. Kang, Carson C. Thoreen, Mario Niepel, Dalia Ercan, Peng Gao, Kenneth D. Westover, Jinhua Wang, Nicholas P. Kwiatkowski, Yan Liu, Wooyoung Hur, Xin Zhang, Sivapriya Kirubakaran, Chunxiao Xu, Qingsong Liu
Rok vydání: 2023
Popis: PDF file - 719K, Supplemental figure 1. Torin2 on PC-3 wide type cell line, the IB was made after 30 min treatment of drug at indicated concentrations. Supplemental figure 2. Torin1, Torin2, AZD8055 and BEZ235 on HeLa and HCT-116 cell line at different time point with a dose responsive drug treatment. Supplemental figure 3. PET-CT experiment of short term treatment of drugs. Supplemental figure 4. PDG-PET determination of drug treatment response with statistics
Databáze: OpenAIRE